October 3, 2018 Gregory Gorgas CEO Artelo Biosciences, Inc. 888 Prospect Street Suite 210 La Jolla, CA 92037 Re: Artelo Biosciences, Inc. Registration Statement on Form S-1 Filed September 27, 2018 File No. 333-227571 Dear Mr. Gorgas: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action, or absence of action by the staff. Please contact Charlie Guidry, Staff Attorney, at 202-551-3621 with any questions. Sincerely, Division of Corporation Finance Office of Consumer Products